Brand Name : Oryzogen
Model Number : HY100M1
Certification : ISO9001 certificate
Place of Origin : China
MOQ : Negotiation
Price : Negotiation
Payment Terms : T/T
Supply Ability : 1000kg per year
Delivery Time : 3-5 days
Packaging Details : 1g/vial 10g/vial 50g/vial
Source : Rice Grain(Oryza Sativa)
Usage : Cell Culture, stem cell culture, vaccine reseach
Storage and Handling : 2-8℃ for 24 months
EINECS No. : 274-272-6
Sterility test : negative
Abnormal toxicity test : conforms
CAS 70024-90-7 Human Serum Cell Culture Ingredients Animal Component Free
Quick detail
Physiological and Biochemical Properties of rHSA and pHSA
Char. | pHSA | rHSA |
Amino Acids Sequence | Same | Same |
N-terminus | DAHKSEV | DAHKSEV |
C-terminus | KLVAASQAALGL | KLVAASQAALGL |
Glycosylation | No | No |
Molecular Mass(MALDI) | 66.554KD | 66.550KD |
PI | 4.8 | 4.8 |
Drug Binding | Similar | Similar |
Thermal Stability | M/P 65℃ | M/P 65℃ |
Lipid Conjugation | Identical | Identical |
Crystal Structure | Identical | Identical |
Description
In cell culture, the advantages of serum-free medium are:
1. Avoid the serum quality changes from different batches, improve the repeatability of cell culture and experiment results.
2. Avoid the toxic effects and serum-derived contamination from serum to cells.
3. Avoid the impact of serum components in the experimental study.
4. Benefit to the differentiation of cultured cells in vitro.
5. Improvde the target proteins expression level and make the cell products easily purified. rHSA can be used as the nutrition and protein carrier. In addition, rHSA can enhance the viscosity of the medium and protect the cells from mechanical damage. What's more, Healthgen rHSA is derived from rice endosperm, which is animal component free, can avoid the prions or virus contaminants.
Advantages
1. Healthgen Biotechnology Corp. is a private company founded in 2006. We specialize in molecular pharmaceutical technology research and high-tech innovation-oriented product development, which is developing, manufacturing and marketing a series of recombinant proteins and growth factors by rice endosperm platform. We have 400 square meters of research center, in which 30% of the research personnels have doctoral degree and major in different directions of the research and development. Healthgen has strong capability in developing a series of biological products.
2. Healthgen quality control systerm has been certified by ISO 9001:2008 and ensure standardized process as well as qualified products.
3. Healthgen has a professional quality control department, in which 50% of them have master's degree or higher. There are 14 employees in the quality department, 9 of them are in QA and 5 are in QA. All of them have rich experience in analysis research or quality inspection. Half of them have graduated diploma. Every year there are more than 50 training courses, which cover GMP, SOP, specification, hygiene, QA, QC issues, etc.
4. The rice endosperm specific expression platform is easy to be large-scale. The rice endosperm has the protein body, which can keeps proteins stability and bioactivity. At present, the production capacity is almost 1000 kg / year.
Supplemental Description
Human serum albumin has been widely used as plasma expansion reagent. Because of its non-enzymatic activity and no immunogenicity, etc. HSA can also be used as excipient and stabilizer in a variety of pharmaceutical preparations and serum-free cell culture medium component. In addition, HSA is also used as a drug carrier due to its antioxidant properties, thereby conferring drugs better physicochemical properties. At present, most HSA products in the market are directly derived and refined from human plasma.
On the one hand, due to the potential existence of various infectious disease pathogens in the human blood, especially AIDS, hepatitis B and other viruses. Thereby, these virus from human plasma will be brought with HSA to the final products. rHSA produced by gene recombinant technology can effectlively avoid the risks of virus pollution and infection. What’s more, the supply of human blood is limited. Therefore, it’s very urgent to search blood substitutes. The establishment and development of recombinant DNA technology provide an important method for the acquisition of biological materials. In recent years, many researchers have been hotly committed to the recombinant human serum albumin research.
CAS 70024-90-7 Human Serum Cell Culture Ingredients Animal Component Free Images |