1. CAS No.: 70024-90-7
2. Other Names: rHSA, recombinant HAS, RecHSA, Recombinant Albumin
3. Purity: Greater than 99 % as determined by SDS-PAGE
4. Source: Rice Grain (Oryza Sativa)
5. Formulation: rHSA is lyophilized with saline
6. Physical Appearance: Off-white to light beige lyophilized powder
Human serum albumin is the most abundant protein in human plasma.
It can transport hormones, lipds and other molecules and maintain
osmotic pressure. Healthgen Biotech has developed the rice
endosperm cell expression platform (OryzHiExp), which has such advantages: high expression level, safety,
scale-up easily, simple production process and environmental
protection etc. Animal free rHSA is a recombinant human serum
derived from rice grains, and doesn't contain any animal component,
which is much safer than plasma derived HSA.
Healthgen Biotechnology Corp. has been committed in research of
protein purification, meanwhile our technology has been patented by
the US Patent and Trademark Office on May 15th 2015 and been
granted the patent of "A method for isolating and purifying
recombinant human serum albumin from transgenic rice grain", which
patent number is US9, 023,990. Now, our rHSA purity can be as high
Human serum albumin is derived from human plasma, which is
collected from different human bodies. So we cannot guarantee the
stability of human serum albumin from different batches. Because of
this, it is difficult to apply to large-scale application in
vaccine production and cell culture. However, Healthgen uses
State-of-the-art platform, having high capacity to express proteins
and peptides in the rice grain. The platform uses rice endosperm
cells as a bioreactor to specifically and highly express various
recombinant proteins and small peptides. By using homozygous rice
as the raw material, with the world's top production process,
Healthgen can maximize the stability of albumin batches to meet the
needs of industrial production.
Physiological and Biochemical Properties of rHSA and pHSA
|Amino Acids Sequence||Same||Same|
Healthgen quality control system has been certified by ISO
9001:2008 and ensure standardized process as well as qualified
Healthgen has a professional quality control department, in which
50% of them have master's degree or higher. There are 14 employees
in the quality department, 9 of them are in QA and 5 are in QA. All
of them have rich experience in analysis research or quality
inspection. Every year there are more than 50 training courses,
which cover GMP, SOP, specification, hygiene, QA, QC issues, etc.
We strictly control the quality of our products to ensure that all
products into the market will be in line with quality standards.
Healthgen has a series of instruments, which are listed as below.
|Osmotic pressure detector||Tianjin SMC30C-1|
|Kjeldahl apparatus||Jinan K9840|
|Karl fischer moisture meter||Mettler Toledo|
|Atomic absorption instrument||PE|